LCB01-0371……..new oxazolidinone has improved activity against Gram-positive...
LCB01-0371 LegoChem Biosciences (South Korea) Phase I, Gram-positive LCB01-0371 is being developed by LegoChem Bio. This new oxazolidinone has improved activity against Gram-positive pathogens and...
View ArticleBC-3781……A Pleuromutilin by Nabriva (Austria) in phase 2
BC-3781 Topical pleuromutilin antibiotic agent Gram-positive, including MRSA, PHASE 2 COMPLETED Nabriva (Austria) BC-3781 The pleuromutilin BC-3781 belongs to the first generation of pleuromutilins...
View ArticleRadezolid in phase 2,Rib-X Pharmaceuticals
Radezolid 869884-78-6 cas no http://www.ama-assn.org/resources/doc/usan/radezolid.pdf 869884-78-6, RX-103, RX-1741, RX-O1_667, Radezolid (USAN/INN), UNII-53PC6LO35W Molecular Formula: C22H23FN6O3...
View ArticlePosizolid
POSIZOLID 252260-02-9 CAS NO (5R)-3-[4-[1-[(2S)-2,3-Dihydroxypropanoyl]-3,6-dihydro-2H-pyridin-4-yl]-3,5-difluorophenyl]-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one AstraZeneca (Originator)...
View ArticleMoringa Oleifera Kills 97% of Pancreatic Cancer Cells in Vitro
Moringa Oleifera Kills 97% of Pancreatic Cancer Cells in Vitro: A hot-water extract of moringa leaves was shown to kill up to 97% of human pancreatic cancer cells (Panc-1) after 72 hours in this...
View ArticleMicuRx Pharmaceuticals (USA) has MRX I IN PHASE 1 for resistant Gram-positive...
MRX I MRX-I 1112968-42-9 cas no C18 H15 F3 N4 O4 4(1H)-Pyridinone, 2,3-dihydro-1-[2,3,6-trifluoro-4-[(5S)-5-[(3-isoxazolylamino)methyl]-2-oxo-3-oxazolidinyl]phenyl]- IN...
View ArticleTuberculosis: the drug development pipeline at a glance.
Tuberculosis: The drug development pipeline at a glance Review Article Pages 1-16 Baptiste Villemagne, Céline Crauste, Marion Flipo, Alain R. Baulard, Benoit Déprez, Nicolas Willand Graphical...
View ArticleEPEREZOLID
EPEREZOLID pfizer.originator CAS NO 165800-04-4 Eperezolid [USAN], PNU 100592, U-100592, Molecular Formula: C18H23FN4O5 Molecular Weight: 394.397423...
View ArticleSUTEZOLID for Treatment of tuberculosis
Sutezolid 168828-58-8 N-({(5S)-3-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]-2-oxo-oxazolidin-5-yl}methyl) acetamide (S)—N-[[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide...
View ArticleGold Nanoparticles Made to Heat Up from Near-Infrared Light for Tumor Killing
Originally posted on lyranara.me: Gold has been a popular material to make nanoparticles because of its biocompatibility, but to get it to do some neat tricks isn’t enough to simply produce spherical...
View ArticleRanbezolid from Ranbaxy as an oxazolidinone antibacterial
Ranbezolid 392659-39-1 hydrochloride 392659-38-0 (free base) N-{[(5S)-3-(3-Fluoro-4-{4-[(5-nitro-2-furyl)methyl]-1-piperazinyl}phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide...
View ArticleBC-7013 a Topical pleuromutilin antibiotic agent from Nabriva
BC-7013 (topical) [14-O-[(3-Hydroxymethyl-phenylsulfanyl)-acetyl]-mutilin] Pleuromutilins Nabriva Gram-positive poster……….https://jmilabs.com/data/posters/ICAAC2009/F1-1521.pdf BC-7013...
View ArticleValnemulin
Valnemulin 101312-92-9, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl- 5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro- 3a,9-propano-3aH-cyclopenta[8]annulen-8-yl-...
View ArticleMK 2048 an HIV integrase inhibitor from Merck
MK 2048 Molecular Formula: C21H21ClFN5O4 Molecular Weight: 461.873943 869901-69-9, 3oyl, 3oyn Merck & Co., Inc....
View ArticleATL1102 for MS – Toxicology Study Main Findings
Sequence Type: DNA fragment CTGAGTCTGTTTTCCATTCT ATL 1102 The antisense oligonucleotide is complementary to a region in the 3′UTR of human ITGA4 (integrin alpha 4) cDNA whose sequence is...
View ArticleMG 96077 in Pre-Clinical for Gram-negative bacteria
MG 96077 poster MG96077 - MethylGene ………..http://methylgene.solocom.biz/files/2011/10/poster102.pdf ……………..lot of data presented Mirati Therapeutics (USA) Pre-Clinical for Gram-negative bacteria...
View ArticleACH-702 the isothiazoloquinolone in preclinical from Achillion...
ACH-702 7-[3(R)-(2-Aminopropan-2-yl)pyrrolidin-1-yl]-9-cyclopropyl-6-fluoro-8-methoxy-2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione...
View ArticleCenicriviroc in Phase 2 for HIV by Takeda/Tobira
Cenicriviroc TAK-652; TBR-652 1-Benzazocine-5-carboxamide, 8-[4-(2-butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl]phenyl]-, (5E)-...
View ArticleANTHONY CRASTO’S NEW DRUG APPROVALS TOUCHES 2 LAKH VIEWS IN 179 COUNTRIES
ANTHONY CRASTO’S NEW DRUG APPROVALS TOUCHES 2 LAKH VIEWS IN 179 COUNTRIES DR ANTHONY MELVIN CRASTO Ph.D WORLDDRUGTRACKER, NEW DRUG APPROVALS OTHERS Eurekamoments in Organic Chemistry NEW DRUG...
View ArticleGlenmark’s novel molecule ‘GRC 27864’ for chronic inflammatory diseases...
Glenmark’s novel molecule ‘GRC 27864’ for chronic inflammatory diseases including pain entering human trials GRC 27864 is a potent, selective, orally bioavailable inhibitor of mPGES-1 The molecule...
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