Clik here to view.
Novel lead compounds in pre-clinical development against African sleeping...
Novel lead compounds in pre-clinical development against African sleeping sickness Med. Chem. Commun., 2017, 8,1872-1890 DOI: 10.1039/C7MD00280G, Review Article Michael Berninger, Ines Schmidt, Alicia...
View ArticleClik here to view.
BMS-986020
BMS-986020 AM-152; BMS-986020; BMS-986202 cas 1257213-50-5 Chemical Formula: C29H26N2O5 Molecular Weight: 482.536...
View ArticleClik here to view.
Enclomiphene citrate, New patent, WO 2017182097, F.I.S. – FABBRICA ITALIANA...
Enclomiphene citrate, New patent, WO 2017182097, F.I.S. – FABBRICA ITALIANA SINTETICI S.P.A WO-2017182097 F.I.S. – FABBRICA ITALIANA SINTETICI S.P.A CARUANA, Lorenzo; (IT). PADOVAN, Pierluigi; (IT)....
View ArticleClik here to view.
FDA approves new treatment for adults with mantle cell lymphoma
FDA approves new treatment for adults with mantle cell lymphoma The U.S. Food and Drug Administration today granted accelerated approval to Calquence (acalabrutinib) for the treatment of adults with...
View ArticleClik here to view.
Secnidazole, секнидазол , سيكنيدازول , 塞克硝唑 ,
Secnidazole Molecular FormulaC7H11N3O3 Average mass185.180 Da 1-(2-Methyl-5-nitroimidazol-1-yl)-2-propanol 1H-Imidazole-1-ethanol, α,2-dimethyl-5-nitro- [ACD/Index Name] 222-134-0 [EINECS] 3366-95-8...
View ArticleClik here to view.
FDA approves first treatment Zelboraf (vemurafenib)for certain patients with...
FDA approves first treatment for certain patients with Erdheim-Chester Disease, a rare blood cancer The U.S. Food and Drug Administration today expanded the approval of Zelboraf (vemurafenib) to...
View ArticleClik here to view.
Ubrogepant, MK-1602
Ubrogepant, MK-1602 (S)-N-((3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-3-yl)-2′-oxo-1′,2′,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3′-pyrrolo[2,3-b]pyridine]-3-carboxamide...
View ArticleClik here to view.
Nefopam Hydrochloride, Нефопама Гидрохлорид, 塩酸ネホパム
Nefopam Molecular Formula C17H19NO Average mass 253.339 Da Cas 13669-70-0 [RN] 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl- 237-148-2 [EINECS]...
View ArticleClik here to view.
Pracinostat
Pracinostat Molecular Formula C20H30N4O2 Average mass 358.478 Da 2-Propenamide, 3-[2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-, (2E)- 929016-96-6 [RN] SB939...
View ArticleClik here to view.
FDA approves Mepsevii (vestronidase alfa-vjbk) for treatment for rare genetic...
FDA approves treatment for rare genetic enzyme disorder The U.S. Food and Drug Administration today approved Mepsevii (vestronidase alfa-vjbk) to treat pediatric and adult patients with an inherited...
View ArticleClik here to view.
TAFAMIDIS
Tafamidis Molecular Formula C14H7Cl2NO3 Average mass 308.116 Da TAFAMIDIS, Fx-1006A PF-06291826 2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid 594839-88-0 [RN] 6-Benzoxazolecarboxylic acid,...
View ArticleClik here to view.
FDA approves new treatment Hemlibra (emicizumab-kxwh) to prevent bleeding in...
FDA approves new treatment to prevent bleeding in certain patients with hemophilia A The U.S. Food and Drug Administration today approved Hemlibra (emicizumab-kxwh) to prevent or reduce the frequency...
View ArticleClik here to view.
Takeda’s Peripherally selective noradrenaline reuptake inhibitor
1-{[(6S,7R)-7-(4-Chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid Molecular Formula C18H18ClFN2O4 Average mass 380.798 Da CAS 1372185-97-1 CAS 1372180-09-0...
View ArticleClik here to view.
Copanlisib
Copanlisib, BAY 80-6946, BAY 84-1236 Molecular FormulaC23H28N8O4 Average mass480.520 Da Cas 1032568-63-0 [RN] 1402152-26-4 MONO HCL UNII-WI6V529FZ9 FDA Approved September 2017...
View ArticleClik here to view.
The synthesis, biological evaluation and structure–activity relationship of...
CAS 74102-02-6 Molecular Formula: C15H17NO3 Molecular Weight: 259.305 g/mol 2-(((2-hydroxyphenyl)amino)methylene)-5,5-dimethylcyclohexane-1,3-dione (39): White solid; m.p. 249 o C; TLC Rf value, 0.48...
View ArticleClik here to view.
FDA approves first two-drug regimen for certain patients with HIV, Juluca...
FDA approves first two-drug regimen for certain patients with HIV The U.S. Food and Drug Administration today approved Juluca, the first complete treatment regimen containing only two drugs to treat...
View ArticleClik here to view.
Palladium-catalyzed direct C-H ethoxycarbonylation of 2-aryl-1,2,3-triazoles...
Palladium-catalyzed direct C-H ethoxycarbonylation of 2-aryl-1,2,3-triazoles and efficient synthesis of suvorexant Org. Chem. Front., 2018, Advance Article DOI: 10.1039/C7QO00945C, Research Article...
View ArticleClik here to view.
VOXELOTOR
VOXELOTOR GBT 440; GTx-011, Treatment of Sickle Cell Disease RN: 1446321-46-5 UNII: 3ZO554A4Q8 Molecular Formula, C19-H19-N3-O3, Molecular Weight, 337.3771 Benzaldehyde,...
View ArticleClik here to view.
FDA approves first biosimilar Herceptin (trastuzumab) for the treatment of...
FDA approves first biosimilar for the treatment of certain breast and stomach cancers Ogivri, a biosimilar to the cancer drug Herceptin, is approved for HER2+ breast cancer and metastatic stomach...
View ArticleClik here to view.
LL 3858, SUDOTERB
LL 3858, SUDOTERB UNII-SK2537665A; CAS 676266-31-2; N-[2-methyl-5-phenyl-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]pyrrol-1-yl]pyridine-4-carboxamide;...
View Article