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FDA Breakthrough Therapy Designation: 32 And Counting

Reblogged from Orphan Druganaut Blog: On February 3rd, GlaxoSmithKline (GSK) announces that Promacta (US)/Revolade (Europe) (Eltrombopag) receives the coveted FDA Breakthrough Therapy Designation...

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How to Handle Drug Polymorphs… Case Study of Trelagliptin Succinate

Pharmaceutical API Polymorphs… case study of Trelagliptin CASE STUDY WITH Compound I having the formula WO2008067465A1 OR US8084605  IS THE PATENT USED AND WITH FORM “A” AND AMORPHOUS FORM Active...

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Lysosomal Storage Disorders: Advocacy Group Receives FDA Orphan Designations

Reblogged from Orphan Druganaut Blog: This is the second Blog Post in a series over the next week that will examine Lysosomal Storage Disorders (LSDs) in the rare disease and orphan drug space. This...

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Biogen’s multiple sclerosis drug Tecfidera obtains EU approval

US-based Biogen Idec has received approval from the European Commission (EC) for its Tecfidera (dimethyl fumarate) as a first-line oral treatment for people with relapsing-remitting multiple sclerosis...

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FDA grants breakthrough therapy designation to Promacta (EU trade name:...

Earlier this week, Ligand Pharmaceuticals Inc. ( LGND ) announced that the U.S. Food and Drug Administration (FDA) granted breakthrough therapy designation to Promacta (EU trade name: Revolade)....

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Eluxadoline …Diarrhea-predominant irritable bowel syndrome

Eluxadoline 5 JAN 2014 Furiex Pharmaceuticals Inc.  more than doubled in its best day of trading after its experimental drug alleviated diarrhea and abdominal pain caused by irritable bowel syndrome...

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FONDAPARINUX

FONDAPARINUX Fondaparinux is a drug belonging to the group of the antithrombotic agents and are used to prevent deep vein thrombosis in patients undergoing orthopedic surgery. It is also used for the...

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Why FDA Supports a Flexible Approach to Drug Development

    By: Margaret A. Hamburg, M.D. We all know that just as every person is different, so too is every disease and every drug. And so we weren’t surprised by the results of a new study published in the...

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IDRAPARINUX… Sanofi (PHASE III)

IDRAPARINUX Nonasodium...

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HEPARIN SODIUM

HEPARIN SODIUM LAUNCHED 1937 9041-08-1 NA SALT 9005-49-6 (heparin) Thromboliquine, Calciparine, Certoparin, Dalteparin, Fraxiparin, Heparinate, Multiparin, Novoheparin, Parnaparin Unfractionated...

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Idrabiotaparinux for anticoagulant therapy.

Idrabiotaparinux  抗血栓治療中の出血率を低下させるためのイドラビオタパリナックスの使用 (biotinylated idraparinux, SSR-126517, SSR-126517E) Idrabiotaparinux has an attached biotin moiety at the non-reducing end unit, which allows its...

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Triphala : A Digestive Miracle

  Emblica officinalis Triphala (/triːˈfɑːlə/ or /triːˈfælə/; Hindi/Sanskrit: त्रिफला, triphalā [trɪˈpʰɐlaː], “three fruits”)[1] is an Ayurvedic[2] herbal rasayana formula consisting of equal parts of...

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ERTUGLIFLOZIN

ERTUGLIFLOZIN, PFIZER THERAPEUTIC CLAIM Treatment of type 2 diabetes CHEMICAL NAMES 1. β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- 2....

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Scientists develop potential new drug treatment to tackle viruses

Originally posted on lyranara.me: An international team of scientists have successfully developed a novel compound which early signs suggest might prevent a range of viruses from infecting humans....

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Fiduxosin ….An α1-Adrenoceptor antagonist

Fiduxosin Fiduxosin hydrochloride, 208992-74-9,   NCGC00162178-02,  AC1L58WW, A-185980.1,ABT-980,UNII-W9O92HYT6I Molecular Formula: C30H30ClN5O4S Molecular Weight: 592.1083...

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Flow chemistry approaches directed at improving chemical synthesis

  Flow synthesis offers many advantages when applied to the processing of difficult or dangerous chemical transformations. Furthermore, continuous production allows for rapid scale up of reactions...

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Tadalafil (cialis)

Tadalafil GF-196960, IC-351, Cialis 6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione...

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Grape Seeds Fight Bowel Cancer

Originally posted on lyranara.me: University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as...

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FDA Approves Vimizim to Treat Mucopolysaccharidosis Type IVA

STRUCTURAL FORMULA Monomer APQPPNILLL LMDDMGWGDL GVYGEPSRET PNLDRMAAEG LLFPNFYSAN 50 PLCSPSRAAL LTGRLPIRNG FYTTNAHARN AYTPQEIVGG IPDSEQLLPE 100 LLKKAGYVSK IVGKWHLGHR PQFHPLKHGF DEWFGSPNCH FGPYDNKARP...

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IkB kinase inhibitors , SANOFI, for osteoarthritis

K salt monohydrate, N-​[[2-​[2-​(methylamino)​-​4-​pyrimidinyl]​-​1H-​indol-​5-​yl]​carbonyl]​-​3-​(phenyl-​2-​pyridinylamino)​-   L-​Alanine, 2-{[2-(2-methylamino-pyrimidin-4-yl)-lH-indole-5-...

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