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Researchers discover how cancer ‘invisibility cloak’ works
Originally posted on lyranara.me: Researchers at National Jewish Health have discovered how a lipid secreted by cancer tumors prevents the immune system from mounting an immune response against it....
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The US FDA has issued full approval for Israeli drugmaker Teva’s Synribo...
Omacetaxine mepesuccinate 高三尖杉酯碱 Alkaloid from Cephalotaxus harringtonia; FDA approved orphan drug status for Ceflatonin in the treatment of chronic myeloid leukemia due to being an inducer of...
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The secret of fertile sperm
Originally posted on lyranara.me: Progesterone and other fatty signaling molecules are critical for sperm fertility. Credit: C. Cain To better understand the causes of male infertility, a team of Bay...
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MOXIFLOXACIN, Bay-12-8039
MOXIFLOXACIN Bay-12-8039 US FDA:link CAS 354812-41-2 186826-86-8 HYDROCHLORIDE 1-cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo- quinoline-3-carboxylic acid...
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FDA Breakthrough Therapy Designation: Fourth Drug Receives FDA Approval
Originally posted on Orphan Druganaut Blog: . The FDA approves on February 12, the fourth drug to have the coveted Breakthrough Therapy Designation (BTD). The approval is for orphan drug Imbruvica...
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Sonidegib/Erismodegib..Novartis Cancer Drug LDE225 Meets Primary Endpoint in...
Sonidegib/Erismodegib CODE DESIGNATION ..LDE225, NVP-LDE-225 Treatment of medulloblastoma PHASE3 2014 FDA FILING Treatment of advanced basal cell carcinoma PHASE3 2014 FDA FILING Treatment of SOLID...
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Cinnamon cuts blood glucose levels in diabetes patients
Originally posted on lyranara.me: Consumption of cinnamon is associated with favorable reductions in plasma glucose and lipid levels, according to research published in the September/October issue of...
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FDA Accepts Filing of NDA for IV Antibiotic Oritavancin with Priority Review
Oritavancin (4R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-arabinohexopyranosyl)-N3-(p-(p-chlorophenyl)benzyl)vancomycin (3S, 6R, 7R, 22R, 23S, 26S, 36R, 38aR) -22 – (3-Amino-2...
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KW-4490 A PDE4 inhibitor from Kyowa Hakko Kirin
KW 4490 cis-4-Cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)cyclohexanecarboxylic Acid Cyclohexanecarboxylic acid, 4-cyano-4-(2,3-dihydro-8-methoxy-1,4-benzodioxin-5-yl)-, cis-...
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Immune cells regulate blood stem cells
Originally posted on lyranara.me: Blood stem cell cultures: Blood stem cells from colonies (cell clusters) in vitro consisting of different blood cells. Nine blood stem cell colonies are illustrated...
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Vertex Pharmaceuticals: Another Step Forward For Kalydeco
Originally posted on Orphan Druganaut Blog: . On February 21st, Vertex Pharmaceuticals announces that the FDA approves a supplemental New Drug Application (sNDA) for orphan drug Kalydeco (Ivacaftor)...
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RAMELTEON, TAK 375 ..Melatonin MT1/MT2 receptor agonist
RAMELTEON ACN-S001714, ZINC00007031 HSDB 7787 Ramelteon Rozerem TAK-375 UNII-901AS54I69 Molecular Formula: C16H21NO2 Molecular Weight: 259.34344 CAS number 196597-26-9...
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Regulatory Considerations for Biosimilars
Biological medicines are already becoming an increasingly important part of health care. With patent expiries on originator biological products, biosimilars are also increasingly become a part of this...
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FDA Approves BMS Drug for Rare Fat Disorder
CHEMICAL NAMES 1. Leptin (human), N-methionyl- 2. N-methionylleptin (human) STRUCTURAL FORMULA MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL 50 TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV...
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Bhasma : The ancient Indian nanomedicine
Bhasma : The ancient Indian nanomedicine Dilipkumar pal Department of Pharmaceutical Sciences, Guru Ghasidash Vishwavidyalya (A Central University), Koni, Bilaspur – 495 009, Chhattisgarh India...
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What Does 100% of Your Daily Value of Cholesterol Look Like?
Healthline just published an interesting infograph that gives a visualization of what your daily value of cholesterol looks like. In the graphic, you can see what 300 mg of cholesterol looks like for...
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Scientists discover new drug targets for aggressive breast cancer
Originally posted on lyranara.me: The image shows the aggressive growth of TNBC cells. Credit: Genome Institute of Singapore, A*STAR Scientists at A*STAR’s Genome Institute of Singapore (GIS) led in a...
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FDA Approves Monovisc Injection for Knee Pain
Sodium Hyaluronate 9067-32-7 (sodium salt) MF: C14H22NNaO11 MW: 403.31 26 feb 2014 Anika Therapeutics Inc. announced it has received marketing approval for Monovisc from the U.S. Food and Drug...
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IBRUTINIB 依鲁替尼 A Btk protein inhibitor.
IBRUTINIB 依鲁替尼 A Btk protein inhibitor. 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one...
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Tivorbex (indomethacin); Iroko Pharmaceuticals; For the treatment of acute pain,
Tivorbex (indomethacin); Iroko Pharmaceuticals; For the treatment of acute pain, Approved February of 2014 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid cas 53-86-1...
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