Ramizol
1,3,5-Tris[(1E)-2′-(4′′-benzoic acid)vinyl]benzene] (Ramizol™) TSB-007 CAS 1292817-44-7 MF C33 H24 O6 MW 516.54 Benzoic acid, 4,4′,4”-[1,3,5-benzenetriyltri-(1E)-2,1-ethenediyl]tris-...
View ArticleFDA approves first treatment Noctiva (desmopressin acetate) nasal spray for...
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View ArticleAstellas Pharma Inc. new Glucokinase Activator, ASP ? for Type 2 Diabetes
ASP ? (2R)-2-(4-cyclopropanesulfonyl-3-cyclopropylphenyl)-N-[5-(hydroxymethyl)pyrazin-2-yl]-3-[(R)-3-oxocyclopentyl]propanamide CAS 1174229-89-0 MW C25 H29 N3 O5 S Benzeneacetamide,...
View ArticleTROXACITABINE троксацитабин , تروكساسيتابين , 曲沙他滨 ,
Troxacitabine CAS 145918-75-8 Molecular FormulaC8H11N3O4 Average mass213.191 Da троксацитабин تروكساسيتابين 曲沙他滨 2(1H)-Pyrimidinone, 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-...
View ArticleGDC 0994, Ravoxertinib
GDC 0994 GDC-0994; Ravoxertinib; 1453848-26-4; GDC0994; UNII-R6AXV96CRH; R6AXV96CRH, RG7842; RG-7842; RG 7842 CAS 1453848-26-4...
View ArticleNovartis Kisqali® (ribociclib, LEE011) receives FDA approval as first-line...
Approved based on a first-line Phase III trial that met its primary endpoint of progression-free survival (PFS) at interim analysis due to superior efficacy compared to letrozole alone[1] At this...
View ArticleNEW DRUG APPROVALS BLOG HITS 16 LAKH VIEWS IN 213 COUNTRIES
NEW DRUG APPROVALS BLOG HITS 16 LAKH VIEWS IN 213 COUNTRIESFiled under: BLOGS, Uncategorized Tagged: BLOG, New drug approvals
View ArticleNew paper on Trelagliptin succinate
Trelagliptin succinate, a novel once-weekly oral dipeptidyl peptidase-4 (DPP-4) inhibitor, was approved for the Japanese market on March 26, 2015 Trelagliptin exhibited a better potency against human...
View ArticleFDA approves drug Xadago (Safinamide, сафинамид , سافيناميد , 沙非胺 , ) to...
Safinamide Molecular Formula C17H19FN2O2 Average mass 302.343 Da (2S)-2-[[[4-[(3-Fluorophenyl)methoxy]phenyl]methyl]amino]propanamide 133865-89-1 , сафинамид , سافيناميد , 沙非胺 , EMD-1195686, ZP-034,...
View ArticleFDA approves first treatment Bavencio (avelumab)for rare form of skin cancer
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View ArticleSEN 826
SEN 826 CAS 1160833-51-1 C25 H31 N5 O, 417.55 Methanone, [1-[3-(1-methyl-1H-benzimidazol-2-yl)phenyl]-4-piperidinyl](4-methyl-1-piperazinyl)- CAS HBr SALT 1612250-71-1 WO2009074300 product patent...
View ArticleTRIENTINE HYDROCHLORIDE, 塩酸トリエンチン , 曲恩汀
TRIENTINE Molecular Formula C6H18N4 Average mass 146.234 Da 112-24-3 CAS 曲恩汀, KD-034, MK-0681, MK-681, TECZA, TETA, TJA-250 1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)- 1,8-diamino-3,6-diazaoctane...
View ArticleFDA approves new eczema drug Dupixent (dupilumab)
FDA aes new eczema drug Dupixentpprov 03/28/2017 11:14 The U.S. Food and Drug Administration today approved Dupixent (dupilumab) injection to treat adults with moderate-to-severe eczema (atopic...
View ArticleFDA approves new drug to treat multiple sclerosis Ocrevus (ocrelizumab)
FDA approves new drug to treat multiple sclerosis 03/29/2017 On March 28, the U.S. Food and Drug Administration approved Ocrevus (ocrelizumab) to treat adult patients with relapsing forms of multiple...
View ArticleDebio-1452
Debio-1452, AFN 1252 AFN-1252; UNII-T3O718IKKM; API-1252; CAS 620175-39-5; CHEMBL1652621; (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide...
View ArticleThe greening of peptide synthesis
The greening of peptide synthesis Stefan B. Lawrenson,a Roy Arava and Michael North*a *Corresponding authors aGreen Chemistry Centre of Excellence, Department of Chemistry, University of York,...
View ArticleEnantioselective synthesis of a cyclobutane analogue of Milnacipran
(1R,2S)-2-(Aminomethyl)-N,N-diethyl-1 phenylcyclobutanecarboxamide (19) 1 H NMR (CDCl3) δ 7.36–7.33 (m, 4H), 7.25–7.21 (m, 1H), 3.51–3.43 (qd, J = 13.8 Hz, 6.8 Hz, 1H), 3.15–2.87 (m, 7H), 2.81–2.72...
View ArticleProcess Development and Good Manufacturing Practice Production of a...
(S)-4-(2,4-Dihydroxyphenyl)-N-(1-phenylethyl)piperidine-1-carboxamide (1) In a………………….. to yield crude 1 (3.51 kg, 77%, 97.7 A% purity). Recrystallization: In a 100 L double jacketed reactor were...
View ArticleEVP 4593
EVP4593; EVP 4593; EVP-4593 M.Wt 356.42 545380-34-5; QNZ (EVP4593); QNZ; 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline; N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine; Formula C₂₂H₂₀N₄O CAS No...
View ArticleGLGP 1837
GLGP 1837 CAS 1654725-02-6 MF C16 H20 N4 O3 S, MW 348.42 For cystic fibrosis treatment N-(3-carbamoyl-5,5,7,7-tetramethyl-4H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-5-carboxamide...
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