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Pravastatin
Pravastatin Sodium CAS : 81131-70-6 (bR,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt sodium...
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ML-236B, Mevastatin (compactin)
Mevastatin (compactin, ML-236B) is a hypolipidemic agent that belongs to the statins class. It was isolated from the mold Penicillium citrinum by Akira Endo in the 1970s, and he identified it as a...
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Alternative solvents can make preparative liquid chromatography greener
Green Chem., 2015, Advance Article DOI: 10.1039/C5GC00887E, Paper Yao Shen, Bo Chen, Teris A. van Beek...
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Determining Criticality-Process Parameters and Quality Attributes
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Determining Criticality-Process Parameters and Quality Attributes Part I: Criticality as a Continuum A practical roadmap in three parts that...
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Inna Ben-Anat, Global QbD Director of Teva Pharmaceuticals
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: Meet Inna Ben-Anat, Global QbD Director of Teva Pharmaceuticals. Inna is a key thought leader in Quality by Design for generics....
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Aseptic Manufacturing Operation: Chinese Company Zhuhai United Laboratories...
Originally posted on DRUG REGULATORY AFFAIRS INTERNATIONAL: see...
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9-(5-oxotetrahydrofuran-2-yl)nonanoic acid methyl ester
9-(5-Oxotetrahydrofuran-2-yl)nonanoic acid methyl ester Name 9-(5-Oxotetrahydrofuran-2-yl)nonanoic acid methyl ester Synonyms Name in Chemical Abstracts 2-Furannonanoic acid, tetrahydro-5-oxo-,...
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Moexipril
Moexipril CAS 103775-10-6 (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid Manufacturers’ Codes: RS-10085...
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Necessity of Establishing Chemical Integrity of Polymorphs of Drug Substance...
Necessity of Establishing Chemical Integrity of Polymorphs of Drug Substance Using a Combination of NMR, HPLC, Elemental Analysis, and Solid-State Characterization Techniques: Case Studies Kamlesh D....
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Pemirolast
Pemirolast (INN) is a mast cell stabilizer used as an anti-allergic drug therapy. It is marketed under the tradenames Alegysal and Alamast. 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido-[1,...
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Critical Assessment of Pharmaceutical Processes, A Rationale for Changing the...
Critical Assessment of Pharmaceutical ProcessesA Rationale for Changing the Synthetic Route Mike Butters ,*† David Catterick ,*‡ Andrew Craig ,‡ Alan Curzons ,‡ David Dale ,§ Adam Gillmore ,*§Stuart...
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Practical Process Research and development; Development..Optimizing the...
Practical Process Research & Development 2000, Pages 165–184 Chapter 8 – Optimizing the Reaction by Minimizing Impurities Neal G. Anderson Process Solutions L.L.C., Nicasio, California The goals...
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BOCEPREVIR
BOCEPREVIR 110-120 °C Handelsname: Victrelis®, Patentnummer: WO2002008244 CAS394730-60-0 Schering Corporation...
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Honokiol, from magnolia bark, shuts down cancer cells in lab
Magnolia virginiana Honokiol, from magnolia bark, shuts down cancer cells in lab Compound in magnolia may combat head and neck cancers Honokiol, from magnolia bark, shuts down cancer cells in lab...
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VILAZODONE SPECTRAL DATA
VILAZODONE Vilazodone hydrochloride; 163521-08-2; Vilazodone HCl; Viibryd; UNII-U8HTX2GK8J; EMD-68843 NO SYNTHESIS IS THIS POST, ONLY SPECTRAL DATA DISCUSSED ENJOY THE INTERPRETATIONS Vilazodone...
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TENELIGLIPTIN
TENELIGLIPTIN Teneligliptin; 760937-92-6; UNII-28ZHI4CF9C; Teneligliptin (INN); 28ZHI4CF9C MF C22H30N6OS MW 426.5782 g/mol Teneligliptin (INN; trade name Tenelia) is a pharmaceutical drug for the...
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GOSOGLIPTIN
GOSOGLIPTIN CAS 869490-23-3 FREE BASE DIHYDROCHLORIDE..869490-47-1 GOSOGLIPTIN; UNII-GI718UO477; PF-00734200; PF-734200;...
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EVOGLIPTIN
EVOGLIPTIN CAS: 1222102-29-5 FREE HCL……1246960-27-9 tartare.. 1222102 -51-3 Dong-A Pharmaceutical. Co., Ltd, 동아제약 주식회사 2-Piperazinone,...
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TRELAGLIPTIN
1 TRELAGLIPTIN Trelagliptin succinate (SYR-472) 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2, 4-dioxopyrimidin-1-yl]methyl]-4-fluorobenzonitrile; butanedioic acid...
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GEMIGLIPTIN
GEMIGLIPTIN 1-[2(S)-Amino-4-[2,4-bis(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one PHASE 3, DPP-IV inhibitor, Lg Life Sciences Ltd. CAS...
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